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Theo de Witte Selected Research

Multiple Myeloma

8/2013Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients.
6/2013Autologous/reduced-intensity allogeneic stem cell transplantation vs autologous transplantation in multiple myeloma: long-term results of the EBMT-NMAM2000 study.
2/2013Association of disparities in known minor histocompatibility antigens with relapse-free survival and graft-versus-host disease after allogeneic stem cell transplantation.
7/2012Superiority of the triple combination of bortezomib-thalidomide-dexamethasone over the dual combination of thalidomide-dexamethasone in patients with multiple myeloma progressing or relapsing after autologous transplantation: the MMVAR/IFM 2005-04 Randomized Phase III Trial from the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
8/2011Tandem autologous/reduced-intensity conditioning allogeneic stem-cell transplantation versus autologous transplantation in myeloma: long-term follow-up.
3/2010Partial T cell-depleted allogeneic stem cell transplantation following reduced-intensity conditioning creates a platform for immunotherapy with donor lymphocyte infusion and recipient dendritic cell vaccination in multiple myeloma.
1/2010Unrelated stem cell transplantation after reduced intensity conditioning for patients with multiple myeloma relapsing after autologous transplantation.
11/2007Peripheral blood or bone marrow cells in reduced-intensity or myeloablative conditioning allogeneic HLA identical sibling donor transplantation for multiple myeloma.

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Theo de Witte Research Topics

Disease

38Myelodysplastic Syndromes (Myelodysplastic Syndrome)
11/2021 - 03/2002
29Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2021 - 03/2002
25Neoplasms (Cancer)
11/2020 - 03/2002
17Leukemia
01/2016 - 03/2002
8Multiple Myeloma
08/2013 - 11/2007
6Graft vs Host Disease (Graft-Versus-Host Disease)
01/2018 - 03/2003
4Hematologic Neoplasms (Hematological Malignancy)
01/2019 - 12/2005
4Pathologic Complete Response
12/2015 - 04/2009
4BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
07/2015 - 10/2009
4Primary Myelofibrosis (Myelosclerosis)
05/2014 - 11/2007
3Lymphoma (Lymphomas)
10/2014 - 04/2009
3B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
06/2012 - 11/2008
3Hematologic Diseases (Blood Diseases)
10/2009 - 12/2008
2Anemia
01/2019 - 03/2016
2Iron Overload
03/2016 - 12/2008
2Refractory Anemia
12/2015 - 10/2014
2Chromosome Aberrations (Chromosome Abnormalities)
10/2014 - 01/2014
2Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria)
10/2011 - 07/2011
2Fibrosis (Cirrhosis)
02/2011 - 11/2007
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
09/2010 - 07/2004
1Drug-Related Side Effects and Adverse Reactions
10/2021
1Treatment-Resistant Schizophrenia
10/2021
1Neutropenia
10/2021
1Hepatomegaly
10/2021
1Hyponatremia
10/2021
1Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome)
10/2021
1Hypoalbuminemia
10/2021
1Bronchiolitis Obliterans Syndrome
01/2018
1Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
01/2017
1Carcinogenesis
03/2016
1Monosomy
01/2016
1Body Weight (Weight, Body)
10/2014
1Essential Thrombocythemia
05/2014
1Polycythemia Vera
05/2014
1Fatigue
02/2013
1Crohn Disease (Crohn's Disease)
04/2012
1Rheumatoid Arthritis
04/2012
1Febrile Neutropenia
05/2011

Drug/Important Bio-Agent (IBA)

7IronIBA
01/2021 - 12/2008
5Minor Histocompatibility AntigensIBA
02/2013 - 12/2005
4Cytarabine (Cytosar-U)FDA LinkGeneric
12/2015 - 11/2009
4HLA Antigens (Human Leukocyte Antigens)IBA
10/2014 - 08/2006
3Ferritins (Ferritin)IBA
10/2021 - 12/2013
3Gemtuzumab (Mylotarg)FDA Link
03/2016 - 12/2013
3DecitabineFDA Link
01/2016 - 05/2011
3DNA (Deoxyribonucleic Acid)IBA
08/2014 - 09/2002
3AntigensIBA
08/2013 - 10/2003
2midostaurinIBA
01/2021 - 01/2017
2Bortezomib (Velcade)FDA Link
01/2021 - 07/2012
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2019 - 10/2017
2Busulfan (Busulfex)FDA Link
07/2017 - 11/2007
2Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
12/2015 - 11/2009
2Messenger RNA (mRNA)IBA
08/2014 - 08/2013
2Daunorubicin (Cerubidine)FDA LinkGeneric
01/2014 - 11/2009
2Etoposide (VP 16)FDA LinkGeneric
01/2014 - 11/2009
2Chelating AgentsIBA
12/2013 - 12/2008
2SurvivinIBA
08/2013 - 09/2005
2Dexamethasone (Maxidex)FDA LinkGeneric
07/2012 - 09/2010
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2012 - 06/2010
216-iodo-3-methylhexadecanoic acid (MIHA)IBA
01/2011 - 11/2010
1treosulfanIBA
11/2021
1Antipsychotic Agents (Antipsychotics)IBA
10/2021
1Clozapine (Clozaril)FDA LinkGeneric
10/2021
1tipifarnib (R115777)IBA
01/2021
1Hemoglobins (Hemoglobin)IBA
01/2019
1Transferrin Receptors (Transferrin Receptor)IBA
01/2018
1Growth Differentiation Factor 15IBA
01/2018
1Transferrin (beta 2 Transferrin)IBA
01/2018
1Clofarabine (Clolar)FDA Link
01/2017
1Lenalidomide (CC 5013)FDA Link
01/2017
1Hydroxyurea (Hydrea)FDA LinkGeneric
03/2016
1Reactive Oxygen Species (Oxygen Radicals)IBA
03/2016
1Melphalan (Alkeran)FDA LinkGeneric
10/2014
1Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
10/2014
1Tyrosine Kinase InhibitorsIBA
09/2014
15-hydroxymethylcytosineIBA
08/2014
1Interleukin-2 (IL2)IBA
01/2014
1B-Cell Maturation AntigenIBA
08/2013
1Thalidomide (Thalomid)FDA Link
07/2012
1Infliximab (Remicade)FDA Link
04/2012
1eculizumabFDA Link
10/2011
1Natural Killer Cell ReceptorsIBA
07/2011
1Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
07/2011

Therapy/Procedure

36Stem Cell Transplantation
01/2018 - 03/2002
22Transplantation
01/2020 - 08/2006
17Hematopoietic Stem Cell Transplantation
01/2020 - 06/2006
14Drug Therapy (Chemotherapy)
01/2021 - 06/2006
10Therapeutics
11/2021 - 03/2002
5Cell Transplantation
11/2021 - 02/2013
5Remission Induction
11/2020 - 01/2014
5Autologous Transplantation
10/2014 - 01/2010
4Erythrocyte Transfusion
01/2020 - 03/2016
4Homologous Transplantation
07/2017 - 11/2007
4Immunotherapy
08/2013 - 10/2003
3Chelation Therapy (Therapy, Chelation)
01/2020 - 12/2008
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2020
1Haploidentical Transplantation
01/2019
1Combination Drug Therapy (Combination Chemotherapy)
01/2014
1Activities of Daily Living (ADL)
02/2013
1Cardiopulmonary Bypass (Heart-Lung Bypass)
10/2011